Thanks to an increase in modern-world toxins, not to mention the day-to-day stresses of normal cellular processes, our liver is exposed to heavier toxin loads and could use a little extra support.

When toxins are not converted into easily removable compounds within the liver, they can stay around in the body longer and may take an alternative route to the brain, nerves, various glands, or other biological tissues—all of which can lead to health implications down the road. (Yikes!)

As the body’s primary detoxification organ, the liver takes the brunt of the body’s toxic burden.

Liver supplements are designed to aid the liver’s detoxifying actions, so it can help filter, bind, and remove unwanted compounds efficiently and effectively. Many liver supplements include antioxidant ingredients because they help remove not only toxins, but free radicals as well (some of which are a byproduct of healthy liver function).* 

Pros: Supports your body against environmental and internal stressors*, Supports the detoxification processes of the liver, kidneys, lungs, gut, and skin,* Combats oxidative stress and promotes binding, filtering, and removal of toxins,* Nutrient + botanical + bioactive combination formula

Cons: Not formulated for children

With a curated entourage of powerful bioactives, botanicals, and nutrients, mbg's daily detox+ delivers 360-degree, whole-body detoxification support. Our premium formula actively fuels detox pathways, promotes toxin filtering and removal, and combats oxidative stress thanks to its synergistic and innovative design. Setria® glutathione (aka the master antioxidant) is at the helm, cruising tissues to clear toxins and restore equilibrium, while each additional ingredient synergizes glutathione by promoting its synthesis (milk thistle), bolstering healthy levels in the body (acerola vitamin C), helping to activate vital enzymes (selenium), and promoting regeneration (NAC). Consider daily detox+ your personal cleanup crew that works round the clock to support your body's 24/7 detoxification. Did we mention it's vegan and free of GMOs, gluten, soy, dairy, and all major food allergens?*

Pros: Supports healthy liver function*, Array of botanicals

Cons: Contains soy allergen, Plastic bottle

Pros: Supports immune and central nervous systems*, Six unique mushroom species, Dissolvable in liquid

Cons: Single use pouches aren’t the most eco-friendly option

Pros: Support the body’s natural detoxification pathways*, Protect the liver from cellular stress*

Cons: 4 capsule serving size, Plastic bottle

Pros: Supports liver health & function*, Assists in toxin elimination*

Cons: Long list of “other ingredients”, Plastic container

Pros: Dual support for liver and GI detoxification*, With amino acids, botanicals, and bioactives

Cons: Not suitable for children, Plastic bottle

Pros: USDA certified organic whole foods blend​​, Supports detoxification and promotes a healthy gut microbiome,* Can be combined with a liquid of your choice, as a topper, or garnish

Cons: Earthy vs. sweet flavor

We don't mean to brag, but mbg's vegan greens powder delivers a USDA-certified organic whole foods blend with 31 powerhouse ingredients that promote digestion, gastrointestinal health, and detoxification. With everything from organic root and sea vegetables, leafy greens, and herbs to berries, digestive enzymes, and pre- and probiotics, organic veggies+ offers a full array of botanicals and fiber to support liver and whole-body detoxification. Cruciferous veggies broccoli and green cabbage and anti-inflammatory ginger and turmeric are especially showing your liver some love.*

Pros: Helps maintain healthy liver function*, Certified B Corporation

Cons: Intended for short-term use, Proprietary blend (dose of each active is unclear)

Pros: Supports liver tissue, function, and detox*, Potent liver-protective botanical extract*

Cons: Not suitable for children

Pros: Assists with natural cleansing pathways in body*, Features some organic ingredients

Cons: Must keep refrigerated after opening, Intended for short-term us

The liver is a large vital organ located in the abdomen that performs over 500 biological tasks to promote everything from healthy skin, digestion, and detoxification to sufficient energy levels.

As the body's primary detox organ, the liver eliminates toxins we take in from our environment and lifestyle (e.g., chemicals, pollutants, heavy metals, alcohol, etc.) by biotransforming them into water-soluble compounds that can be excreted through urine and by incorporating fat-soluble compounds into bile for elimination via feces.

While many detox products are designed to be a temporary solution or "cleanse" for a season, they're often tough on the body and their benefits are fleeting.

Unlike detox drinks and liquid cleanse diet fads, the best liver detox supplements help bolster liver health and function 24/7 with targeted bioactives to promote liver and whole-body detoxification pathways.*

The liver and its functions can be somewhat elusive to the average person, but you better believe that your liver is working hard every day to filter compounds for the rest of the body to use (or easily eliminate). 

We know how confusing the dietary supplement market can be, so we asked our vice president of scientific affairs, Ashley Jordan Ferira, Ph.D., RDN, to highlight the top five criteria to consider when choosing the best liver detox supplement.

Detoxification is complex—and the liver is right in the middle of it all.

Choosing a comprehensive liver detox supplement that supports various aspects and angles of detoxification (such as detox phase I and II, which occur in the liver) and helps the body bind to and remove toxins is key. 

Products that contain antioxidants (especially glutathione, aka the body's "master antioxidant") help maintain oxidative balance, which is crucial for optimal liver function.* 

Although the liver is a biological detox VIP, detoxification is a whole-body process that involves multiple organ systems. 

Naturally, your detox supplement should have ingredients (e.g., nutrients, botanicals, and bioactives) that provide comprehensive support that aids cellular, organ, and whole-body cleanup activities.* 

The vast majority of short-term, overhaul cleanses simply don't make sense (and can be quite taxing on mental health and psychological well-being). "Our bodies detox 24/7, so why the heck aren't we supporting that?" asks Ferira. 

Most of the detox supplements included on our list are meant to be taken every day and provide daily detoxification support.* 

When it comes to dietary supplements, quality and transparency are of the utmost importance.

If you're thinking about adding a liver detox supplement (or any new supplement) to your routine, make sure you do your research on the company's sourcing, quality, and reputation. 

The product should prioritize purity and potency, and the brand should be transparent about what's in itstheir product and where it comes from.

While daily supplementation can help bolster detoxification, promoting optimal liver health and function is a 24/7 endeavor.*

The liver certainly isn't the only detoxification organ, but it's no doubt the most famous.

You'll notice that this list of supplements doesn't have one go-to ingredient to support liver health but rather a smorgasbord of bioactives that promote liver detoxification from every angle.* 

If you're thinking about adding one of these liver supplements to your daily routine for everyday detox support, make sure to talk to a health care provider first.

Whether you're using this guide to navigate the vast market of liver supplements or are already sold on one included in this list, we hope you find the detox product that complements your lifestyle and takes care of your liver health needs.*