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Vitamin D Helps Women 50+ Balance Adipokine Hormones (Great For Blood Sugar & Weight)

Image by Julia Volk / Stocksy
November 16, 2022

You may think adding more physical movement to your weekly routine, getting good sleep, eating a well-balanced diet, and proper hydration are the best (or maybe even only?) ways to optimize your metabolism. But what if I told you that something as simple as taking a vitamin D supplement can help promote healthy body composition and regulate blood sugar levels? *

In a new randomized clinical trial from Menopause, healthy women between 50 and 65 that took a daily vitamin D supplement for nine months demonstrated healthier levels of adiponectin and resistin (two key adipokine hormones that play an important role in insulin sensitivity, body composition, and healthy inflammatory actions) compared to the control group.*

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What are adiponectin & resistin?

First things first—what are adipokine hormones, and how do they impact metabolic health? 

Adipokines are hormones secreted from adipose tissue (aka fat tissue) that play a part in key metabolic actions (e.g., insulin regulation and energy homeostasis), cardiovascular actions, and immune functions.

Adiponectin is directly tied to fat burn—low levels help store fat while normal (higher) levels burn it. It also promotes a healthy inflammatory response and proper blood flow through arteries, making it an all-around helpful hormone for metabolic health.

Resistin is tied to suboptimal inflammatory status, insulin resistance, and higher LDL ("bad") cholesterol levels. Unlike adiponectin, you don't want high amounts of this adipokine—maintaining low levels is key to supporting metabolic and heart health.

How vitamin D promotes hormone & blood sugar balance.

After nine months of vitamin D supplementation, participants saw a 19% increase in adiponectin levels and a 32% decrease in resistin levels. Balancing these hormones is beneficial for a wide range of metabolic health factors (e.g., body composition, insulin sensitivity, blood sugar balance, and cardiovascular health).

It's also worth noting that women supplementing with vitamin D saw a 45% increase in vitamin D serum levels (a big win, considering 29% of U.S. adults are deficient in this essential nutrient!), while the placebo group saw a 19% decrease in serum levels. This further bolsters supplementation as an effective method for achieving truly optimal vitamin D levels (which is likely higher than you think) as measured by serum total 25-hydroxyvitamin D levels in your blood.

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The takeaway.

Taking a quality vitamin D supplement each day delivers myriad health benefits—including supporting healthy adipokine hormone balance that's linked to blood sugar balance, healthy weight maintenance, and optimal cardiovascular health.* 

Consider mindbodygreen's vitamin D3 potency+ for your daily dose of D—its efficacious dosage (5,000 IU), superior form (D3), and bioavailability (i.e., built-in organic oils that aid absorption) make it a truly effective tool for supporting healthy vitamin D levels and overall metabolic health.*

If you are pregnant, breastfeeding, or taking medications, consult with your doctor before starting a supplement routine. It is always optimal to consult with a health care provider when considering what supplements are right for you.
Morgan Chamberlain
Morgan Chamberlain
mbg Supplement Editor

Morgan Chamberlain is a supplement editor at mindbodygreen. She graduated from Syracuse University with a Bachelor of Science degree in magazine journalism and a minor in nutrition. Chamberlain believes in taking small steps to improve your well-being—whether that means eating more plant-based foods, checking in with a therapist weekly, or spending quality time with your closest friends. When she isn’t typing away furiously at her keyboard, you can find her cooking in the kitchen, hanging outside, or doing a vinyasa flow.