Bioactive B Vitamins Are Critical For Promoting Brain Health — Here's Why
So, what if I told you there's a good chance your body can't utilize the B's in your supplement efficiently? Unfortunately, bioavailability isn't considered in many supplement formulas that include B vitamins, even though it should be top priority.
Why you should choose bioactive and methylated B vitamins.
However, when supplements feature B vitamins that are already in their bioactive forms (and for folate and vitamin B12, that means their methylated forms), folks with an MTHFR gene variant are getting nutrients they can readily use in cells and organs throughout their body (yes, including your brain).
And remember, 50% of people have these gene variations but most don't even know it. Since bioavailable B vitamins have no downside for individuals that don't have a variant, it's always a good idea to make sure the B's you're taking are bioactive and ready to go (just in case).
Here's a comprehensive list of the exact bioactive B vitamin forms to look for:
- B1: thiamin mononitrate
- B2: riboflavin-5-phosphate
- B3: niacinamide
- B5: D-calcium pantothenate
- B6: pyridoxal-5-phosphate
- B7: D-biotin
- B9: (6S)-5-methyltetrahydrofolic acid (e.g., as Quatrefolic®)
- B12: methylcobalamin
How methylated B's support whole-body health.
B vitamins are also essential for healthy methylation, and methylation plays a critical role in cognitive health and performance. To support a healthy methylation cycle, central nervous system, and overall well-being, taking a supplement with methylated, bioactive B's—particularly, folate, riboflavin, and vitamins B6 and B12—is a no-brainer.*
Bioactive B vitamins are so important for supporting the methylation cycle, cognitive function, and mental well-being—especially for folks with MTHFR gene variations.*
Morgan Chamberlain is a supplement editor at mindbodygreen. She graduated from Syracuse University with a Bachelor of Science degree in magazine journalism and a minor in nutrition. Chamberlain believes in taking small steps to improve your well-being—whether that means eating more plant-based foods, checking in with a therapist weekly, or spending quality time with your closest friends. When she isn’t typing away furiously at her keyboard, you can find her cooking in the kitchen, hanging outside, or doing a vinyasa flow.