Not Sleeping Enough Can Lead To Oxidative Stress In Women, Study Shows

Sometimes it seems like there are a lot of differing opinions among health professionals. Is coconut oil good or bad? Should you do more cardio or strength training? Those answers can be pretty nuanced and vary based on the person asking them. But the one thing pretty much every health professional can agree on is that we all need to get enough quality sleep1 each night. Period.  

Obviously, that’s easier said than done, especially for women. Fluctuating hormone levels2, long work hours, caring for babies or aging parents, and stress are all just a few factors that impact our shut-eye over the years. And even if you feel like sleeping less isn’t affecting you, it likely is starting to take a toll on you internally—especially on your heart health. 

According to a new study published in the journal Scientific Reports, sleeping 90 minutes less than your norm every night can lead to signs of oxidative stress in the blood vessels3 of 30- and 40-year-old women in as few as six weeks. 

Researchers of this study were particularly interested in looking at the impact of mild sleep restriction measures of oxidative stress in endothelial cells—the cells that line blood vessels. 

Why? Well, blood vessels comprise the body’s vascular system, which is responsible for delivering oxygen-rich blood to every part of the body and sweeping away waste products. While the heart provides the force needed for blood to move throughout the body, the health of individual blood vessels also significantly impacts the brain. 

Blood vessels are susceptible to damaging oxidative stress (aka an imbalance of beneficial antioxidants to harmful free radicals). This is a major risk factor for heart disease—the leading cause of death in women4. 

By understanding how a common experience many women in their 30s and 40s have (periods of not sleeping enough) on a common risk factor of the number one killer of women, we can take a more targeted approach to reducing that risk. 

So a total of 35 women (who, on average, were 36 years old) who regularly slept seven to nine hours a night completed this two-part study. For six weeks, they followed their regular sleep schedule. For another six weeks, they had their bedtime delayed by an hour and a half (bringing their sleep time to about six hours a night). 

This combination of inflamed and dysfunctional cells and a lack of quality control from antioxidants is the first step in cardiovascular disease. 

"This is some of the first direct evidence to show that mild chronic sleep deficits cause heart disease," study leader Sanja Jelic, M.D. said in a press release. 

The findings of this study further illustrate the importance of getting enough sleep (and enough quality sleep) for women. While some sleep-disrupting situations just can’t be avoided in life—thinking specifically of new parents here—getting seven to nine hours of sleep is a goal that is well within reach for most.