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Why Musclespan Is The Latest Longevity Metric To Watch

Ava Durgin
Author:
September 03, 2025
Ava Durgin
Assistant Health Editor
By Ava Durgin
Assistant Health Editor
Ava Durgin is the Assistant Health Editor at mindbodygreen. She is a recent graduate from Duke University where she received a B.A. in Global Health and Psychology. In her previous work, Ava served as the Patient Education Lead for Duke Hospital affiliated programs, focusing on combating food insecurity and childhood obesity.
Image by Jacob Lund / iStock
September 03, 2025

While we've long been fixated on lifespan (how long we live) and healthspan (how long we live well), a new metric is emerging that could revolutionize how we think about aging and vitality: musclespan.

Coined by Gabrielle Lyon, D.O., musclespan represents the duration your skeletal muscles remain strong, functional, and healthy throughout your life. This isn't just another fitness trend; it's a science-backed approach to longevity that positions muscle health as the foundation of healthy aging.

Understanding musclespan: More than just muscle mass

The distinction between muscle mass and musclespan is crucial. Muscle mass simply measures how much muscle tissue you currently possess. Musclespan, however, focuses on the longevity of that muscle's strength and functionality over time.

Think of it this way: you might build impressive muscle mass during a six-month training program, but if you don't maintain it sustainably, your musclespan remains short. The goal isn't temporary gains but sustained muscle health that supports you through decades of life.

This concept represents a fundamental shift from viewing muscle as merely aesthetic to understanding it as a critical organ system. Your skeletal muscle functions as your body's largest metabolic organ, actively communicating with other systems through signaling molecules called myokines that influence everything from immune function to cognitive health.

Why musclespan matters particularly for women

Women face unique challenges when it comes to muscle health, making musclespan especially relevant. Hormonal changes throughout life, particularly during perimenopause and menopause, accelerate muscle loss. Yet many women still prioritize weight loss over strength building, missing a crucial opportunity for long-term health.

Skeletal muscle serves as your body's metabolic powerhouse. It's the primary site for glucose storage and utilization, making it essential for maintaining insulin sensitivity. This is particularly important for preventing metabolic conditions like prediabetes and fatty liver disease, which disproportionately affect women as they age.

Strong muscles also provide disease and injury resilience. They support mobility, reduce fall risk, and enhance recovery from illness or surgery. Beyond physical benefits, muscle tissue actively produces compounds that support mood regulation and cognitive function, contributing to overall quality of life.

Musclespan is gaining traction (& we’re here for it)

The growing interest in musclespan reflects evolving scientific understanding of muscle's role in aging. Research consistently shows that muscle decline often begins subtly in your 30s, long before obvious signs of frailty appear. This makes early intervention crucial.

Lyon and other longevity experts emphasize that skeletal muscle functions like a critical organ system, vital for metabolism, immune function, and successful aging. This perspective has given rise to related concepts like "strengthspan,1" which specifically measures how long you maintain functional strength.

These new paradigms challenge traditional health metrics by positioning muscular longevity as a cornerstone of well-being. Instead of focusing solely on cardiovascular health or body weight, this approach recognizes that muscle health underlies virtually every aspect of physical function.

Improve your musclespan today

Understanding musclespan is one thing; implementing it is another. The concept encourages a proactive approach to strength training that views resistance exercise not as optional but as essential medicine for aging well.

This means prioritizing compound movements that build functional strength, ensuring adequate protein intake to support muscle protein synthesis, and viewing strength training as a long-term investment rather than a short-term goal. It also means measuring success differently, tracking strength gains, functional improvements, and how you feel rather than just focusing on aesthetic changes.

The takeaway

The musclespan approach recognizes that the muscles you build and maintain today become the foundation for your mobility, independence, and vitality in the decades to come. By shifting focus from temporary gains to sustainable muscle health, you're investing in a future where aging doesn't mean declining.

This paradigm shift represents more than just a new way to think about fitness; it's a blueprint for redefining what healthy aging looks like.