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4 Science-Backed Diets That Could Cut Your Dementia Risk By 28%

Ava Durgin
Author:
August 25, 2025
Ava Durgin
Assistant Health Editor
By Ava Durgin
Assistant Health Editor
Ava Durgin is the Assistant Health Editor at mindbodygreen. She is a recent graduate from Duke University where she received a B.A. in Global Health and Psychology. In her previous work, Ava served as the Patient Education Lead for Duke Hospital affiliated programs, focusing on combating food insecurity and childhood obesity.
woman cutting a cucumber in kitchen
Image by Charday Penn / iStock
August 25, 2025

Women have a significantly higher lifetime risk of developing Alzheimer's disease than men, yet new research reveals they also have the most power to prevent it through diet. 

A recent study tracking over 130,000 people for more than 13 years just uncovered evidence that four specific eating patterns can slash dementia risk by up to 28%. 1

The Mediterranean diet emerged as the frontrunner, but here's the most encouraging finding: women who followed any of these brain-protective diets experienced dramatic cognitive benefits, while men saw limited protection from only one approach. 

This isn't just about eating healthier; it's about understanding that your daily food choices are literally rewiring your brain for the future.

The impact of diet on brain health 

The team evaluated five dietary patterns: 

  • The Mediterranean diet (rich in olive oil, fish, and vegetables)
  • The MIND diet (a brain-focused blend of Mediterranean and DASH diets emphasizing berries and leafy greens)
  • The Recommended Food Score (measuring intake of nutrient-dense whole foods)
  • The Alternative Healthy Eating Index (based on American dietary guidelines)
  • The Dietary Inflammatory Index (tracking foods that promote inflammation).

During the follow-up period, ~1,500 participants developed dementia. This large sample size and extended timeline make the results particularly reliable for understanding how diet affects long-term brain health.

The four diets that protect your brain 

The results were remarkably consistent across multiple healthy eating patterns. People who closely followed the Mediterranean diet reduced their dementia risk by 27%, while the MIND diet lowered risk by 28%. The Recommended Food Score and Alternative Healthy Eating Index both showed 23% risk reductions. 

On the flip side, people eating inflammatory diets, those high in processed foods, refined carbs, and saturated fats, faced a 30% increased dementia risk. This suggests that what you avoid eating may be just as important as what you include.

The protective diets shared key components: plenty of vegetables, fruits, whole grains, fish, nuts, and healthy fats like olive oil, while minimizing processed foods and refined sugars. These foods provide antioxidants and anti-inflammatory compounds that protect brain cells from damage and support healthy blood flow to the brain.

Why women see the biggest brain benefits

The study delivered particularly empowering news for women: every single brain-protective diet showed significant cognitive benefits for female participants. Women who closely followed the Mediterranean diet, MIND diet, anti-inflammatory eating patterns, or high-quality whole food approaches all experienced substantial reductions in dementia risk.

This finding is especially crucial given that women face unique neurological vulnerabilities. After menopause, declining estrogen levels leave women's brains more susceptible to inflammation and oxidative damage. Estrogen normally acts as a powerful neuroprotector, supporting brain cell communication and defending against harmful free radicals.

The research suggests that nutrient-dense, anti-inflammatory foods may help fill this protective gap. Components like omega-3 fatty acids from fish, polyphenols from berries, and healthy fats from olive oil and nuts appear to provide similar neuroprotective benefits to what estrogen once offered. This means that strategic dietary choices could be particularly powerful for women navigating midlife and beyond.

Simple ways to start protecting your brain today

Start by incorporating more brain-protective foods into your current meals:

  • Add a handful of berries to your breakfast: They're packed with anthocyanins that specifically protect brain cells.
  • Use olive oil as your primary cooking fat: Its monounsaturated fats support healthy brain blood flow.
  • Eat fish a few times a week: Omega-3 fatty acids reduce brain inflammation and support memory.
  • Snack on nuts instead of processed foods: They provide healthy fats and vitamin E for brain protection.
  • Load half your plate with vegetables, especially leafy greens that deliver folate and antioxidants.

The beauty of these dietary approaches is their flexibility. You don't need to follow rigid meal plans or eliminate entire food groups. Instead, focus on crowding out inflammatory foods with brain-nourishing options like colorful vegetables, healthy fats, and antioxidant-rich fruits. 

The takeaway

This research provides evidence that you have significant control over your dementia risk through daily food choices. The Mediterranean diet, MIND diet, and other anti-inflammatory eating patterns don't just support general health; they specifically protect your brain from cognitive decline.