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Want Sharper Memory? Research Says Creatine Could Be The Key

Ava Durgin
Author:
September 25, 2025
Ava Durgin
Assistant Health Editor
By Ava Durgin
Assistant Health Editor
Ava Durgin is the Assistant Health Editor at mindbodygreen. She is a recent graduate from Duke University where she received a B.A. in Global Health and Psychology. In her previous work, Ava served as the Patient Education Lead for Duke Hospital affiliated programs, focusing on combating food insecurity and childhood obesity.
Image by Prostock-Studio / iStock Photo
September 25, 2025

Long celebrated for its ability to support muscle strength and recovery, creatine has been a staple among athletes for decades. But emerging research suggests its benefits extend far beyond physical performance—from bone health to brain health.

A systematic review and meta-analysis1 found that creatine supplementation doesn’t just help with reps in the gym; it may also sharpen your mind in measurable ways. And for those of us looking to age well, protect cognition, and keep our brains firing on all cylinders, that’s big news.

The brain benefits of creatine

Here’s what stood out from the analysis:

  • Memory got a boost: Participants supplementing with creatine experienced a 14% improvement in memory performance, translating to better recall and learning capacity.
  • Thinking speed improved: Processing speed, a measure of how quickly the brain reacts, jumped by 19% in those taking creatine.
  • Focus sharpened: Attention span increased by 13%, making it easier to stay on task.
  • Certain groups saw greater gains: The benefits were most notable for women, adults under 60, and people with existing health conditions.

Interestingly, these brain perks showed up whether participants took creatine for just a few weeks or stuck with it longer, suggesting that improvements can happen relatively quickly.

Creatine helps more than muscles

Your brain, like your muscles, depends on a steady supply of cellular energy (in the form of ATP) to function well. Creatine helps replenish ATP, essentially giving neurons more fuel to power memory, focus, and quick thinking. Researchers are now exploring its potential role in protecting against age-related cognitive decline and even delaying diseases linked to brain energy deficits.

The takeaway

Creatine isn’t just for gym rats—it’s shaping up to be a promising ally for cognitive longevity. From boosting memory to speeding up processing power, this well-studied supplement may help your brain stay sharp and resilient as you age.