New Research Finds Link Between Headaches, Migraine & Circadian Rhythm

Our circadian rhythm influences our sleep-wake cycle, including when we feel awake versus sleepy—and according to this study, potentially when headaches strike.

In their meta-analysis of existing research on cluster headaches, migraines, hormones, and circadian rhythm, researchers found many people tend to experience their symptoms at the same time every day.

Namely, 71% of people who experienced cluster headaches had circadian patterns to their headaches, with attacks peaking in the late evening to early hours of the morning, and more attacks during spring and fall. For migraines, 50% of people showed a circadian pattern to their attacks, with the time of day ranging a bit wider, from late morning to early evening.

In terms of hormonal patterns, those with cluster headaches had higher cortisol levels and lower melatonin levels than those without cluster headaches, and those dealing with migraines had lower levels of melatonin in their urine than people without migraines, as well as lower melatonin levels during a migraine attack.

As study author Mark Joseph Burish, M.D., Ph.D. explains in a news release, "The data suggest that both of these headache disorders are highly circadian at multiple levels, especially cluster headache," adding that these findings reinforce the importance of our circadian rhythm and its role in cluster headaches and migraines.

While more research needs to be done to further explain this circadian connection to headaches, it's clear that having a regulated circadian rhythm carries over into many areas of our health and wellbeing. And the good news is, getting your circadian rhythm in check is a simple, effective, and accessible way to take control of your sleep health.

For one thing, the essential sleep rules like going to bed and waking up at the same time every day, are a good place to start—along with avoiding caffeine and alcohol too close to bed, which can impact sleep quality.

It may also be worthwhile to consider opting for a quality sleep supplement with ingredients like magnesium and pharmaGABA, which are research-backed to help regulate circadian rhythm and improve sleep quality. (Here are nine of our favorites, all vetted by a nutrition scientist.)